High-throughput Unmasking of Biological Interactomes with Binding Landscape Emulators (HUBBLE)

Estimated Value: $15,000,000
Open 14 days left VirginiaAerospace & Defensesolicitation
Oct 8, 2026
Nov 5, 2026 3:00 PM
Aerospace & Defense
solicitation
541714
AI Summary
DARPA is seeking proposals to develop a computational tool for mapping all protein-protein interactions. The goal is to create an in-silico capability that can identify new diagnostic and therapeutic targets, particularly for conditions like traumatic brain injury. Winning proposals will need to demonstrate a robust and comprehensive approach to biological interactome mapping.
Line Items
ItemQtyUnitEst. Unit PriceEst. TotalCategory
Research and Development for In-Silico Protein-Protein Interaction Mapping Capability 1 project $10,000,000.00 $10,000,000.00 Professional Services
Demonstration and Validation of Diagnostic and Therapeutic Target Identification for Traumatic Brain Injury 1 project $5,000,000.00 $5,000,000.00 Professional Services
Estimated Bid Value$15,000,000.00

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📎 DARPA-PA-27-01.pdf View
📎 Attachment_B_DARPA-PA-26-10__Model_OT_for_Research_HUBBLE_20261008.docx View
📎 Attachment_F_Risk_Matrix_HUBBLE.pptx View
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