Chemical, Biological, Radiological, and Nuclear (CBRN) Medical Countermeasure (MCM) Participant Basic Agreement (PBA)

Estimated Value: $500,000,000
Open New MarylandComputer Hardwareother
Oct 21, 2026
—
Computer Hardware
other
541714
AI Summary
This is an open announcement for a Participant Basic Agreement (PBA) to establish a network of pre-qualified partners for the development, testing, and fielding of Chemical, Biological, Radiological, and Nuclear (CBRN) Medical Countermeasures (MCMs). The government seeks innovative solutions for both host-targeted resilience and threat-targeted neutralization, as well as advanced diagnostic capabilities and decision support tools to protect warfighters.
Line Items
ItemQtyUnitEst. Unit PriceEst. TotalCategory
Development of Host-Targeted Resilience Medical Countermeasures (Investigational Drugs) 1 project $50,000,000.00 $50,000,000.00 Medical
Development of Threat-Targeted Neutralization Medical Countermeasures (Drugs/Biologics) 1 project $50,000,000.00 $50,000,000.00 Medical
Development of Rapid, Effective Patient Diagnostics for CBRN Threats (Pathogen/Agent-based) 1 project $25,000,000.00 $25,000,000.00 Medical
Development of Rapid, Effective Patient Diagnostics for CBRN Threats (Host-based) 1 project $25,000,000.00 $25,000,000.00 Medical
Development of Pre-exposure Prophylactic Countermeasures 1 project $30,000,000.00 $30,000,000.00 Medical
Development of Post-exposure Prophylactic Countermeasures 1 project $30,000,000.00 $30,000,000.00 Medical
Development of Acute Treatment Countermeasures 1 project $30,000,000.00 $30,000,000.00 Medical
Development of Ruggedized Formulations for CBRN MCMs 1 project $20,000,000.00 $20,000,000.00 Medical
Development of Novel Drug Delivery Systems for CBRN MCMs (e.g., oral, intranasal, autoinjector) 1 project $20,000,000.00 $20,000,000.00 Medical
Development of Adaptable Platform Technologies for Rapid Threat Response 1 project $40,000,000.00 $40,000,000.00 Medical
Research and Development Services for Neurological Protection Mechanisms 1 project $15,000,000.00 $15,000,000.00 Professional Services
Research and Development Services for Respiratory Stabilization Mechanisms 1 project $15,000,000.00 $15,000,000.00 Professional Services
Research and Development Services for Immune Modulation Mechanisms 1 project $15,000,000.00 $15,000,000.00 Professional Services
Research and Development Services for Hematologic and Vascular Function Mechanisms 1 project $15,000,000.00 $15,000,000.00 Professional Services
Research and Development Services for Cellular Stress and Repair Pathways 1 project $15,000,000.00 $15,000,000.00 Professional Services
FDA Licensure/Clearance Support for CBRN MCMs 1 service $20,000,000.00 $20,000,000.00 Professional Services
Rapid Prototyping Services for CBRN MCMs 1 service $10,000,000.00 $10,000,000.00 Professional Services
Late-Stage Development Services for CBRN MCMs 1 service $30,000,000.00 $30,000,000.00 Professional Services
Testing and Evaluation Services for CBRN MCMs 1 service $25,000,000.00 $25,000,000.00 Professional Services
Estimated Bid Value$500,000,000.00

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📎 Medical_Countermeasure_PBA_SAM_Announcement_updated_21Oct2026.pdf View
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