Generative Unconstrained Intelligence Drug Engineering (GUIDE) collaboration between U.S. interagency, academic and industry partners

Open 726 days left MarylandComputer Hardwareother
Sep 23, 2026
Oct 18, 2028 4:00 PM
Computer Hardware
other
541715
AI Summary
This solicitation is for the Generative Unconstrained Intelligence Drug Engineering (GUIDE) program, which seeks U.S. interagency, academic, and industry partners to collaborate on an integrated computational and experimental platform for accelerating medical countermeasure development. Interested entities should submit an email demonstrating technical relevancy in medical countermeasure development to the primary points of contact to be considered for participation under a Participant Basic Agreement (PBA). Projects will be awarded under specific U.S.C. authorities, not FAR-based regulations.
Line Items
ItemQtyUnitEst. Unit PriceEst. TotalCategory
Participation in Generative Unconstrained Intelligence Drug Engineering (GUIDE) Program 1 lot — — Professional Services
Development of advanced simulation and machine learning capabilities for drug engineering 1 project — — IT Services
Research and development of biological products (e.g., monoclonal antibodies, vaccines) 1 project — — Medical
Research and development of small molecule drugs 1 project — — Medical
Optimization of critical quality attributes (safety, efficacy, manufacturability, pharmacokinetics/pharmacodynamics) for medical countermeasures 1 project — — Professional Services
Development of computational platforms for drug discovery and design 1 project — — IT Services
Experimental validation and testing of medical countermeasures 1 project — — Medical

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